Absorption, distribution, metabolism, and excretion of dirlotapide in the dog
| Autor: | A. J. Bessire, D. A. Merritt, J. P. Sams, A. D. Vaz, M. P. Lynch |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Indoles Administration Oral Absorption (skin) Urine Biology Beagle Excretion Dogs Internal medicine medicine Animals Bile Tissue Distribution Carbon Radioisotopes Feces Pharmacology Kidney Gastrointestinal tract General Veterinary Dirlotapide medicine.anatomical_structure Endocrinology Female Anti-Obesity Agents Carbamates medicine.drug |
| Zdroj: | Journal of Veterinary Pharmacology and Therapeutics. 30:17-23 |
| ISSN: | 1365-2885 0140-7783 |
| DOI: | 10.1111/j.1365-2885.2007.00865.x |
| Popis: | Three once-daily oral doses of 0.2 mg/kg [(14)C]dirlotapide were administered to beagle dogs to study the absorption, distribution, metabolism, and excretion of dirlotapide. Mean (14)C recovered at 2.5 and 4.5 h after the last dose was 90%. Mean (14)C in urine, bile, and feces was |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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