Comparative Characteristics of the Morphology of Rabbit Lymph Nodes after Implantation of Porous Titanium with Composite Nanocoating and Hydroxyapatite Particles Embedded into Pores

Autor: M. A. Smetankina, D.G. Bliznets, N. S. Kiselyova, N. B. Krokhina, E. B. Makarova, A.P. Rubstein
Rok vydání: 2011
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 151:488-491
ISSN: 1573-8221
0007-4888
DOI: 10.1007/s10517-011-1364-2
Popis: We studied changes of microarchitectonics of lymph nodes in mature rabbits in response to introduction of bioimplants based on porous titanium with carbon-containing nanocoating or nanocoating with hydroxyapatite embedded into pores. Moderate local reactivity of the lymphoid system was observed in animals with implants coated with carbon-containing films within 30 days after surgery. In animals with nanocoated implants containing hydroxyapatite, the immune response was more pronounced. Introduction of implants led to activation of cellular and humoral mechanisms of immunity in animals of both groups.
Databáze: OpenAIRE