Unexpected cytotoxicity of TiO2-coated magnesium alloys
| Autor: | Phaedra Silva-Bermudez, Benjamín Millán-Ramos, Julieta García-López, Daniela Morquecho-Marín, Cecilia C. Barrera-Ortega, Dietmar Letzig, José Victoria-Hernández, David Ramírez-Ortega, Sandra E. Rodil, Osmary Depablos-Rivera |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Magnesium Mechanical Engineering technology industry and agriculture chemistry.chemical_element 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences chemistry Chemical engineering Mechanics of Materials Biological fluids Degradation (geology) General Materials Science Reactivity (chemistry) 0210 nano-technology Cytotoxicity ddc:620.11 |
| Zdroj: | Morquecho-Marin, D.; Silva-Bermudez, P.; Millan-Ramos, B.; Victoria-Hernandez, J.; Letzig, D.; Ramirez-Ortega, D.; Depablos-Rivera, O.; Garcia-Lopez, J.; Barrera-Ortega, C.; Rodil, S.: Unexpected cytotoxicity of TiO2-coated magnesium alloys. In: Materials Letters. Vol. 276 (2020) 128236. (DOI: /10.1016/j.matlet.2020.128236) |
| ISSN: | 0167-577X |
| DOI: | 10.1016/j.matlet.2020.128236) |
| Popis: | Biodegradable Mg-based alloys have attracted increasing attention from orthopedic surgeons and biomaterials scientists since their Young’s modulus is close to that of bone. However, control of the degradation rate is still a challenge. Sputtered TiO2 coatings were deposited on Mg-Zn-Ca alloys aiming to reduce the initial strong reactivity of Mg with biological fluids. However, the degradation tests indicated that the coated samples induced a larger variation in the pH, greater H2 production and formation of degradation products in comparison to the bare alloys. Consequently, an enhanced cytotoxicity of the coated samples was observed. |
| Databáze: | OpenAIRE |
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