Nonesophageal Eosinophilic Gastrointestinal Disorders: Clinical Care and Future Directions
| Autor: | Sandeep K. Gupta, Sara K. Naramore |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry Gastroenterology Treatment method Disease pathogenesis medicine.disease Article Enteritis 03 medical and health sciences 0302 clinical medicine Quality of life (healthcare) Immune system Gastritis 030220 oncology & carcinogenesis Eosinophilia Pediatrics Perinatology and Child Health Eosinophilic Eosinophilic gastroenteritis medicine Humans 030211 gastroenterology & hepatology Clinical care Prospective cohort study Intensive care medicine business |
| Zdroj: | Journal of Pediatric Gastroenterology & Nutrition. 67:318-321 |
| ISSN: | 1536-4801 0277-2116 |
| Popis: | Eosinophilic gastrointestinal disorders are a set of conditions with a wide range of clinical manifestations and treatment modalities. The disorders are suspected to result from an abnormal inflammatory response to allergen (s), and individuals may develop a relapsing or chronic disease, if the allergen is not eliminated. Mechanisms of disease pathogenesis, including the humoral immune response, need to be fully elucidated. A variety of therapies are used, although there is a lack of well-defined randomized, prospective studies. Other therapeutic options are needed as the current treatments have potential concerns; elimination diets may impair a child's quality of life, and corticosteroids have adverse risks with long-term use. We review what is known about nonesophageal eosinophilic gastrointestinal disorders, and discuss research investigations which need to be conducted to facilitate diagnosis and enhance treatment methods. |
| Databáze: | OpenAIRE |
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