Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum
| Autor: | Tan Lunbo, Jinhui Liu, Jun He, Qing Yang, Anwen Yuan, Daojun Xu, Ting Wei |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
lcsh:Immunologic diseases. Allergy medicine.medical_specialty Article Subject Swine medicine.medical_treatment animal diseases Immunology Antibodies Viral Immunoglobulin G 03 medical and health sciences Immune system fluids and secretions Polysaccharides Pregnancy Epidermal growth factor Internal medicine medicine Animals Immunology and Allergy Insulin-Like Growth Factor I Epidermal Growth Factor biology Colostrum Growth factor food and beverages Astragalus Plant General Medicine In vitro 030104 developmental biology Endocrinology Immunoglobulin M Classical Swine Fever Virus Dietary Supplements biology.protein Female Plant Preparations Antibody lcsh:RC581-607 Research Article |
| Zdroj: | Journal of Immunology Research, Vol 2017 (2017) Journal of Immunology Research |
| ISSN: | 2314-7156 2314-8861 |
| Popis: | Colostrum is the main external resource providing piglets with nutrients and maternal immune molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in vitro and several animal models. This study aimed to determine the effects of APS on immune factors in sow colostrum and milk. The sow diet was supplemented with APS one week before the expected delivery date. Colostrum and milk were collected and designated as 0 h- (onset of parturition), 12 h-, and 24 h-colostrum and 36 h-milk postpartum. Samples were measured using porcine immunoglobulin (Ig) G, IgM, classical swine fever virus antibody (CSFV Ab), epidermal growth factor (EGF), and insulin-like growth factor- (IGF-) 1 ELISA Quantitation Kits. Dietary supplementation of APS significantly enhanced the presence of IgG, IgM, EGF, and IGF-1 in 0 h-colostrum (P<0.001). The blocking rates of CSFV Ab were increased in samples from APS-supplemented sow when compared to those from the matched samples without APS treatment. The results indicate that supplement of APS could improve the immune components in sow colostrum and/or milk; and status of some specific vaccination could be determined through using colostrum or early milk in sow. |
| Databáze: | OpenAIRE |
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