Troublesome heterotopic ossification and stroke: Features and risk factors. A case control study
| Autor: | Alexis Ruet, François Genêt, Claire Jourdan, Alexis Schnitzler, Kambiz Minooee, Philippe Denormandie |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Time Factors Neuroscience (miscellaneous) Risk Factors Epidemiology Ischaemic stroke Developmental and Educational Psychology medicine Retrospective analysis Humans cardiovascular diseases Risk factor Stroke Aged Retrospective Studies business.industry Ossification Heterotopic Case-control study Mean age Middle Aged medicine.disease Surgery Logistic Models Case-Control Studies Female Heterotopic ossification Neurology (clinical) business |
| Zdroj: | Brain Injury. 29:866-871 |
| ISSN: | 1362-301X 0269-9052 |
| DOI: | 10.3109/02699052.2015.1005133 |
| Popis: | To determine the features of stroke-related HO in a large sample of patients and to assess if HO risk is increased by haemorrhagic stroke.A case control study (risk factor of a rare event using retrospective analysis).Sixty-one patients with stroke-81 troublesome HOs-were included, each was matched with four controls, i.e. 244 patients with no HO after stroke. Matching criteria were age (±3.5 years) and sex. Data recorded were time from stroke to surgery, ischaemic or haemorrhagic stroke and presence of HO risk factors.Mean age at time of stroke = 46.02 ± 11.4 years (15.9-76.3) for the case sub-group. Time from stroke to surgery = 23.4 ± 27.8 months (3.6-150.0). There was a significant relationship between haemorrhagic stroke and HO development (OR = 3.01; 95% CI = 1.14-7.98; p 0.05), but not for ischaemic stroke. This became non-significant when all matching and risk factors were included in the model (adjusted OR = 1.98; 95% CI = 0.60-6.54; p = 0.26).Haemorrhagic stroke appears to increase the risk of HO development. Further studies are required to determine if this risk factor is independent from other comorbid factors. |
| Databáze: | OpenAIRE |
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