Renal Tumors in Children and Young Adults Older Than 5 Years of Age
| Autor: | Margaret G. Lamb, Michael Arnold, Sara A. Mansfield, Mark Ranalli, Joseph Stanek, Jennifer H. Aldrink |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Abdominal pain Pediatrics medicine.medical_specialty Adolescent Wilms Tumor Disease-Free Survival 03 medical and health sciences Young Adult 0302 clinical medicine Renal cell carcinoma Carcinoma medicine Humans Young adult Child Survival rate Carcinoma Renal Cell Neoplasm Staging business.industry Histology Wilms' tumor Hematology medicine.disease Kidney Neoplasms Survival Rate Oncology 030220 oncology & carcinogenesis Child Preschool Pediatrics Perinatology and Child Health Cohort Female medicine.symptom business 030215 immunology |
| Zdroj: | Journal of pediatric hematology/oncology. 42(4) |
| ISSN: | 1536-3678 |
| Popis: | Renal masses are most common in children between ages 1 to 3 years, with less known about renal tumors in older children and young adults. The aim of this study was to review the presentation, demographics, histology, and outcomes in patients over 5 years of age with renal tumors compared with younger children. 111 renal tumors were diagnosed in patients 5 years of age and older (median, 7 y; range, 5 to 31 y) between 1950 and 2017 at a single institution. Wilms tumor (WT) was the most common histology in 84 patients (75%), followed by renal cell carcinoma in 12 patients (10.7%). Abdominal pain was the most common presenting symptom (46%) followed by hematuria (28.8%), and a palpable abdominal mass (24.3%). For WT, older children more commonly presented with advanced-stage disease (stages 3 and 4) than younger children (57.7% vs. 11.5%; P |
| Databáze: | OpenAIRE |
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