Primary Fallopian Tube Mullerian Adenosarcoma With Sarcomatous Overgrowth and a Previously Unreported MEIS1-NCOA2 Gene Fusion
| Autor: | Jesse L Hart, Renan Ribeiro E Ribeiro, Katrine Hansen, Eleanor R Lewin, Mohammad Ruhul Quddus |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Abdominal pain
Pathology medicine.medical_specialty Endometriosis Adnexal mass Pathology and Forensic Medicine Fusion gene Nuclear Receptor Coactivator 2 Bloating medicine Mullerian Adenosarcoma Fallopian Tube Neoplasms Humans Pathological Fallopian Tubes Peritoneal Neoplasms business.industry Adenosarcoma Obstetrics and Gynecology medicine.disease medicine.anatomical_structure Uterine Neoplasms Female medicine.symptom Gene Fusion business Fallopian tube |
| Zdroj: | International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 41(1) |
| ISSN: | 1538-7151 |
| Popis: | Extrauterine Mullerian adenosarcomas (MA) are rare and often associated with endometriosis. We report a 55-yr-old patient seen in consultation for abdominal pain and bloating. Imaging was suggestive of a left adnexal mass and "peritoneal carcinomatosis". Pathological examination of the specimen revealed a MA arising in the left fallopian tube, with sarcomatous overgrowth, diffuse peritoneal involvement and omental "caking". Next-generation sequencing identified a MEIS1-NCOA2 gene fusion, previously unreported in MA. |
| Databáze: | OpenAIRE |
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