Passive immunity of progeny from broiler breeders vaccinated with oil-emulsion bacterin against Salmonella enteritidis
| Autor: | Elton Vinicius Sterzo, A. Berchieri, Jacqueline Boldrin de Paiva, A. Y. Inoue, A. Bernardino |
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| Přispěvatelé: | Ft Dodge Anim Hlth, Universidade Estadual Paulista (Unesp) |
| Rok vydání: | 2009 |
| Předmět: |
Veterinary medicine
Time Factors Salmonella Vaccines Salmonella enteritidis medicine.medical_treatment Spleen Passive immunity Biology Immune system Food Animals medicine Animals Colonization broiler breeder Poultry Diseases Salmonella Infections Animal General Immunology and Microbiology Broiler Salmonella Enteritidis Building and Construction Salmonella vaccine vaccination Antibodies Bacterial Vaccination medicine.anatomical_structure passive immunity Animal Science and Zoology Chickens Immunity Maternally-Acquired |
| Zdroj: | Web of Science Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 0005-2086 |
| Popis: | Made available in DSpace on 2013-08-12T18:13:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-12-01 Made available in DSpace on 2013-09-30T19:15:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-12-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T15:31:41Z No. of bitstreams: 0 Made available in DSpace on 2014-05-20T15:31:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2008-12-01 Young poultry are very susceptible to Salmonella Enteritidis (SE) infections because of the absence of complete intestinal flora colonization and an immature immune system. This study evaluated the role of passive immunity on the resistance of young birds against early infections caused by SE. The progeny of broiler breeders vaccinated with an oil-emulsion bacterin was compared to the progeny of unvaccinated birds. Efficacy was determined by challenging birds at 1 and 14 days of age with SE Nal Spc strain, phage type 4. After challenge at 1 day of age, the progeny of vaccinated birds presented a significantly lower number (log(10)) of SE Nal Spc reisolation (P < 0.05) in liver (2.21), spleen (2.31), and cecal contents (2.85) compared with control groups (2.76, 3.02, and 6.03, respectively). The examination of the internal organs, 3 days after infection, revealed that 28% of the birds (7/25) from vaccinated breeders were positive, whereas 100% (25/25) of the chicks derived from unvaccinated birds were positive. Birds challenged at 14 days of age presented a lower number of positive samples compared with those challenged at 1 day of age, and the progeny of vaccinated birds presented statistically lower numbers (log(10)) of colony-forming units/ml of SE Nal Spc only in the cecal contents compared with nonvaccinated breeder progeny (2.11 vs. 2.94). Age seems to influence the susceptibility of birds to SE infections: in control groups, the number of positive birds at 14 days of age (9/25) was lower when compared with the group infected at 1 day of age (25/25). The number of positive fecal samples of the progeny of vaccinated birds was significantly lower (36) than those of the control group (108) after challenge at 1 day of age. Unchallenged progeny of vaccinated birds presented passive antibodies detectable by enzyme-linked immunosorbent assay (ELISA) up to 21 days of age. on the other hand, antibodies of the control group were detected by ELISA 14 days after challenge. These results show a significant contribution of breeder vaccination by increasing the resistance of the progeny against early SE infections. However, the bacteria were not completely eliminated, suggesting that additional procedures are needed to effectively control SE infections. Ft Dodge Anim Hlth, BR-13064798 São Paulo, Brazil São Paulo State Univ, Dept Vet Pathol, Avian Pathol Lab, São Paulo, Brazil São Paulo State Univ, Dept Vet Pathol, Avian Pathol Lab, São Paulo, Brazil |
| Databáze: | OpenAIRE |
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