Effects of long-term Doppler ultrasound exposure on cochlea and cochlear nucleus in prenatal period in an experimental model

Autor: Ertan Zengin, Seda Cinar, Metin Çeliker, Suat Terzi, Tolga Mercantepe, Fatih Oghan, Levent Tumkaya, Abdulkadir Özgür, Fatma Beyazal Çeliker, Emine Demir, Mehmet Beyazal, Engin Dursun, Arzu Turan
Rok vydání: 2021
Předmět:
Zdroj: The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 35(25)
ISSN: 1476-4954
Popis: New generation Doppler ultrasonography (DUSG) application effects on cochlea and cochlear nucleus (CN) are unclear. We aimed to investigate the effects of new generation DUSG application at different frequencies in prenatal period on cochlea and CN in rats.Twenty-four pregnant female rats were divided into three groups (There was no any statistical difference between the groups in respect of histopathologically. USGED group showed mild caspase-3 positive neurons and glial cells. However, there was no significant difference between the USGED and other groups (Multiple administration of new generation DUSG to pregnant rats has not shown harmful effects on the cochlear neural tissue. High frequencies are more sensitive in cochlea to apply DUSG.
Databáze: OpenAIRE