Birth Prevalence of Cerebral Palsy: A Population-Based Study
| Autor: | Marshalyn Yeargin-Allsopp, Alyson B. Goodman, Kim Van Naarden Braun, Nancy S. Doernberg, Laura A. Schieve, Deborah Christensen |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Birth weight Population Ethnic group Gestational Age White People Article Cerebral palsy 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Prevalence medicine Spastic Birth Weight Humans education education.field_of_study business.industry Cerebral Palsy Infant Newborn Gestational age medicine.disease Confidence interval Black or African American Pediatrics Perinatology and Child Health Etiology Female business 030217 neurology & neurosurgery |
| Zdroj: | Pediatrics. 137 |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.2015-2872 |
| Popis: | OBJECTIVE:Population-based data in the United States on trends in cerebral palsy (CP) birth prevalence are limited. The objective of this study was to examine trends in the birth prevalence of congenital spastic CP by birth weight, gestational age, and race/ethnicity in a heterogeneous US metropolitan area.METHODS:Children with CP were identified by a population-based surveillance system for developmental disabilities (DDs). Children with CP were included if they were born in metropolitan Atlanta, Georgia, from 1985 to 2002, resided there at age 8 years, and did not have a postneonatal etiology (n = 766). Birth weight, gestational age, and race/ethnicity subanalyses were restricted to children with spastic CP (n = 640). Trends were examined by CP subtype, gender, race/ethnicity, co-occurring DDs, birth weight, and gestational age.RESULTS:Birth prevalence of spastic CP per 1000 1-year survivors was stable from 1985 to 2002 (1.9 in 1985 to 1.8 in 2002; 0.3% annual average prevalence; 95% confidence interval [CI] −1.1 to 1.8). Whereas no significant trends were observed by gender, subtype, birth weight, or gestational age overall, CP prevalence with co-occurring moderate to severe intellectual disability significantly decreased (−2.6% [95% CI −4.3 to −0.8]). Racial disparities persisted over time between non-Hispanic black and non-Hispanic white children (prevalence ratio 1.8 [95% CI 1.5 to 2.1]). Different patterns emerged for non-Hispanic white and non-Hispanic black children by birth weight and gestational age.CONCLUSIONS:Given improvements in neonatal survival, evidence of stability of CP prevalence is encouraging. Yet lack of overall decreases supports continued monitoring of trends and increased research and prevention efforts. Racial/ethnic disparities, in particular, warrant further study. |
| Databáze: | OpenAIRE |
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