Laparoscopy significantly improves the perceived preoperative stage of gastric cancer
| Autor: | G.V Thomas, Miles C. Allison, Paul Edwards, Wyn G. Lewis, Guy Blackshaw, Jonathan D. Barry |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Cancer Research
medicine.medical_specialty Computed tomography Adenocarcinoma Sensitivity and Specificity Predictive Value of Tests Stomach Neoplasms Surgical oncology medicine Humans Neoplasm Metastasis Stage (cooking) Laparoscopy False Negative Reactions Neoplasm Staging medicine.diagnostic_test business.industry Gastroenterology Reproducibility of Results Cancer General Medicine medicine.disease Clinical trial Oncology Predictive value of tests Radiology Tomography X-Ray Computed business Abdominal surgery |
| Zdroj: | Gastric Cancer. 6:225-229 |
| ISSN: | 1436-3291 |
| DOI: | 10.1007/s10120-003-0257-0 |
| Popis: | The aim of this study was to examine the accuracy of laparoscopy is staging patients with gastric cancer in comparison with preoperative computed tomography (CT) examination.One hundred patients out of a consecutive series of 258 patients with gastric adenocarcinoma underwent a preoperative staging CT followed by a staging laparoscopy. The strengths of the agreement between the CT stage, the laparoscopic stage, and the final histopathological stage were determined by the weighted Kappa statistic (Kw).The strengths of agreement between the CT stage and the final histopathological stage were Kw = 0.336 (95% confidence interval [CI]; 0.172-0.5; P = 0.0001) for T stage and 0.378 (95% CI; 0.226-0.53; P = 0.0001) for M stage, compared with 0.455 (95% CI; 0.301-0.609; P = 0.0001) and 0.73 (95% CI; 0.596-0.864; P = 0.0001) for the laparoscopic T and M stages, respectively. Unsuspected metastases that were not detected by CT, were found in 21 patients at laparoscopy, all of whom had T3 or T4 locally advanced tumors evident on CT.Preoperative laparoscopic staging of gastric cancer is indicated for potential surgical candidates with locally advanced disease in the absence of metastases on CT. The aim of this study was to examine the accuracy of laparoscopy in staging patients with gastric cancer in comparison with preoperative computed tomography (CT) examination. |
| Databáze: | OpenAIRE |
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