Mercapturic acid formation from 2-aminopyrazine in rats
| Autor: | W. H. W. Lunn, J. K. Shadle |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pharmacology
2-aminopyrazine Pyrazine Stereochemistry Health Toxicology and Mutagenesis Metabolite General Medicine Urine Toxicology Biochemistry Oral gavage Mass Spectrometry Acetylcysteine Rats Rats Zucker chemistry.chemical_compound chemistry Oral administration Pyrazines Moiety Animals Mercapturic acid Chromatography High Pressure Liquid |
| Zdroj: | Xenobiotica; the fate of foreign compounds in biological systems. 22(11) |
| ISSN: | 0049-8254 |
| Popis: | 1. The compound 2-aminopyrazine was given by oral gavage to normal rats and their urine collected. 2. A mercapturic acid containing the 2-aminopyrazine moiety was isolated from this urine. This represents the first example of this type of a metabolite from a pyrazine. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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