Prediction of thyroid nodule malignancy using thyroid imaging reporting and data system (TIRADS) and nodule size
| Autor: | Amir Mohammad Ghanei, Mahsa Masjedi Esfahani, Shadi Ebrahimian, Nooshin Afshar Moghadam, Peyman Hashemi, Azin Shayganfar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Thyroid nodules medicine.medical_specialty Cystography FNA biopsy Biopsy Fine-Needle Malignancy Risk Assessment Sensitivity and Specificity 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Biopsy medicine Humans Radiology Nuclear Medicine and imaging Thyroid Neoplasms Thyroid Nodule Retrospective Studies Ultrasonography Suspicious for Malignancy medicine.diagnostic_test business.industry Data Collection Thyroid Nodule (medicine) Middle Aged medicine.disease Cross-Sectional Studies medicine.anatomical_structure Fine-needle aspiration 030220 oncology & carcinogenesis Female Radiology medicine.symptom business |
| Zdroj: | Clinical Imaging. 60:222-227 |
| ISSN: | 0899-7071 |
| DOI: | 10.1016/j.clinimag.2019.10.004 |
| Popis: | Objectives Thyroid imaging reporting and data system (TIRADS) is a combination of ultrasonographic features developed to help physicians in predicting the malignancy risk of thyroid nodules based on sonographic characteristics. Thyroid nodule size is another factor in determining whether a nodule is malignant. The aim of this study was detecting the predictive value of TIRADS and nodule size based on Bethesda classification in prognostication of malignancy. Methods This was a cross-sectional study of 239 patients with thyroid nodules. The patients underwent ultrasonography using TIRADS classification and FNA biopsy based on Bethesda categorization. The results were analyzed using SPSS with the cut off points and predictive values measured. Results TIRADS ≥4 could detect malignant nodules with a sensitivity of 91.67% and specificity of 52.8%. An inverse relationship was observed between nodule size and malignancy risk and cutoff point of 12 mm was found for detecting malignant nodules. Conclusions Thyroid nodules with TIRADS 4 and 5 and diameter lower than 12 mm, are highly suspicious for malignancy and should be considered as indications for fine needle aspiration biopsy. Advances in knowledge The study suggests TIRADS and thyroid nodule size as sensitive predictors of malignancy. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect