Relationship Between Lactate Levels and Length of Hospital Stay in Infants with Lower Respiratory Tract Infection
| Autor: | Selda Seçim, Esra Topal, Emek Uyur Yalçın, Furkan Erdogan, Rabia Gönül Sezer Yamanel |
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| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Intensive Care Units Pediatric 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Internal medicine Lower respiratory tract infection Immunology and Allergy Medicine Humans Lactic Acid Child Respiratory Tract Infections Retrospective Studies Original Research business.industry Mortality rate Respiratory infection Infant Length of Stay medicine.disease Increased lactate 030228 respiratory system Oxygen Saturation Shock (circulatory) Pediatrics Perinatology and Child Health medicine.symptom business Hospital stay |
| Zdroj: | Pediatr Allergy Immunol Pulmonol |
| ISSN: | 2151-3228 |
| Popis: | Background: Increased lactate concentrations are directly related to the severity of shock and mortality rates. There are limited data regarding the prognostic value of lactate among lower respiratory tract infections. We aimed to investigate the impact of lactate levels on admission on the clinical outcomes of children with lower respiratory tract infections. Methods: We performed a retrospective study of hospitalized patients aged 1–12 months. We recorded data on patient demographics, clinical, laboratory, treatment, and outcomes. The primary outcome measure was the length of hospital stay, and the secondary outcome was transfer to the pediatric intensive care unit (PICU) and/or mortality rates. Results: A total of 304 infants were included in the study. There were 198 infants with lactate levels of >2 mmol/L. Lactic acidosis was present in 6 infants, with a mean hospital stay of 8 ± 3 days. Only 1 (0.3%) patient required intubation, and 5 (1.6%) were transferred to the PICU. The overall mortality rate was 0%. Lactate levels (≤2 and >2 mmol/L) were not related to the length of hospital stay, transfer to PICU/discharge, and the need for intubation (P = 0.16, 0.8, and 0.46, respectively). The length of hospital stay was not correlated with lactate levels on admission (r = 0.01, P = 0.84), pCO(2) (r = 0.03, P = 0.52), pH (r = 0.07, P = 0.19), C-reactive protein (r = 0.06, P = 0.28), and oxygen saturation (r = −0.02, P = 0.72). Conclusions: Lactate levels on admission did not predict the length of hospital stay in children with lower respiratory infections and were not related to the need for transfer to the intensive care unit. We suggest using lactate levels in combination with clinical, laboratory, and physical examination findings as predictors of disease severity. |
| Databáze: | OpenAIRE |
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