Crystal Structure and Hydrogen Bonding Study of (10E)-2,2-Dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione 10-Oxime Derived From a-Lapachone
| Autor: | Ari M. da Silva, Aurélio B. B. Ferreira, Marcelo H. Herbst, Andrea Rosane da Silva, Lorenzo C. Visentin |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
crystal structure
Pharmaceutical Science Crystal structure Crystallography X-Ray Chloride oxime Article Analytical Chemistry lcsh:QD241-441 chemistry.chemical_compound Hydroxylamine lcsh:Organic chemistry X-Ray Diffraction Drug Discovery Polymer chemistry Oximes medicine Organic chemistry Molecule Physical and Theoretical Chemistry Fourier transform infrared spectroscopy Nuclear Magnetic Resonance Biomolecular hydrogen bond Ethanol Molecular Structure Hydrogen bond Organic Chemistry Hydrogen Bonding Oxime chemistry Chemistry (miscellaneous) Molecular Medicine medicine.drug Naphthoquinones |
| Zdroj: | Molecules Volume 16 Issue 2 Pages 1192-1200 Molecules, Vol 16, Iss 2, Pp 1192-1200 (2011) |
| ISSN: | 1420-3049 |
| DOI: | 10.3390/molecules16021192 |
| Popis: | The compound (10E)-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10-dione-10-oxime (1) was synthesized from a-lapachone and hydroxylamine chloride in alkaline medium. Single-crystals suitable for X-ray diffraction measurements were grown from an ethanol solution, and the crystal structure of the title molecule is reported for the first time. The title molecule was also characterized by 1H- and 13C-NMR in CDCl3 solution, FTIR and MS. The crystal structure of 1 shows an E stereochemistry and dimers formed through classical hydrogen bonds. |
| Databáze: | OpenAIRE |
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