Post-infectious focal encephalitis due to COVID-19
| Autor: | Abdulla Nasser, Shyam Moudgil, Ashish Bhargava, Elisa Akagi Fukushima |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Pediatrics medicine.medical_specialty General Immunology and Microbiology Coronavirus disease 2019 (COVID-19) Epidemiology business.industry Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Public Health Environmental and Occupational Health Case Report Focal encephalitis medicine.disease Pathophysiology Serology Lesion Infectious Diseases medicine medicine.symptom business Encephalitis Young male |
| Zdroj: | Germs |
| ISSN: | 2248-2997 |
| DOI: | 10.18683/germs.2021.1247 |
| Popis: | Introduction: Several publications described neurological manifestations caused by SARS-CoV-2 Immune-mediated neurological damages caused by COVID-19 are increasingly recognized Case report: A young male presented in March 2020 with a new-onset seizure Later, he started to experience a severe headache During the second admission in May, the MRI of the brain showed left frontal lesion Nasal PCR for SARS-CoV-2 was negative, but the serology was positive, raising the suspicion of immune-mediated encephalitis Elevated cerebrospinal fluid immunoglobulin G with two oligoclonal bands were also seen The patient received IV immunoglobulin and showed improvement in headache Follow-up MRIs of the brain revealed complete resolution of the lesion Discussion: Neurological complications from COVID-19 have been increasingly recognized The proposed pathophysiology is either direct damage of neurological tissues, or indirectly through immunemediated mechanisms The timeline of the patient's presentation with seizure, as well as the lesion on the brain MRI with complete resolution after the IV immunoglobulin, strongly suggest that the patient had immune-mediated encephalitis after exposure to SARS-CoV-2 Conclusions: Several cases of encephalitis caused by SARS-CoV-2 have been reported Immunemediated encephalitis as probable pathophysiology is described here [ABSTRACT FROM AUTHOR] Copyright of Germs is the property of Asociatia Pentru Cresterea Vizibilitatii Cercetarii Stiintifice (ACVCS) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts ) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|