Complete Pathological Response to Chemotherapy for Non-Small Cell Lung Cancer Demonstrated by Gamma Camera Positron Emission Tomography

Autor: K.K. Balan, D. Gilligan, S.E. Old, R.A.R. Coulden
Rok vydání: 2000
Předmět:
Zdroj: Clinical Oncology. 12:53-55
ISSN: 0936-6555
DOI: 10.1007/s001740050009
Popis: We report the case history of a 61-year-old female smoker who presented with an inoperable T2N2M0 squamous cell carcinoma of the right upper lobe bronchus. This was staged by computed tomography (CT), positron emission tomography (PET) using a modified dual-headed gamma camera, and mediastinoscopy. She then underwent three cycles of cisplatin-containing chemotherapy. After the chemotherapy, CT demonstrated a residual 10 mm mass in the right upper lobe and a considerable reduction in size of the mediastinal lymphadenopathy. Functional tumour imaging with PET showed no abnormality, suggesting that there was no remaining viable tumour. At right upper lobectomy a complete pathological response was confirmed. We discuss PET, the potential new applications of gamma camera technology, and the use of cisplatin-containing chemotherapy in non-small cell lung cancer.
Databáze: OpenAIRE