Effect of hydrocortisone on synaptic transmission in surviving rat olfactory cortex slices
| Autor: | Gerasimova Ia, A. A. Mokrushin, N. A. Emel'yanov, Bagaeva Tr |
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| Rok vydání: | 1989 |
| Předmět: |
Nervous system
Synaptic potential Olfactory system medicine.medical_specialty Hydrocortisone General Neuroscience Action Potentials Biology Neurotransmission In Vitro Techniques Inhibitory postsynaptic potential Olfactory Bulb Synaptic Transmission Rats Synapse Endocrinology medicine.anatomical_structure Internal medicine medicine Excitatory postsynaptic potential Animals Pyramidal cell Neuroscience |
| Zdroj: | Neuroscience and behavioral physiology. 19(4) |
| ISSN: | 0097-0549 |
| Popis: | A study has been made of the effect of bath-applied hydrocortisone (10(-4) M) on excitatory transmission of the lateral olfactory tract (LOT), a superficial pyramidal cell synapse of the rat olfactory cortex slice. Populations EPSP and IPSP were depressed for 6-12 min and were then increased (60 min) by hydrocortisone. Recovery of evoked potentials was prolonged (40-60 min) when slices were washed with normal incubation medium. Habituation of synaptic potential during LOT repeated stimulation deteriorated as a result of hydrocortisone application in perfusion solution. The data obtained were considered to represent functions of adaption of the nervous system to a stressor. |
| Databáze: | OpenAIRE |
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