CHildhood Allergy and tolerance: Biomarkers and Predictors (CHAMP) and quality of life

Autor: M. Depner, Eckard Hamelmann, Parastoo Kheiroddin, Erika von Mutius, Andreas Böck, Wolfgang Greiner, Kirsten Beyer, Stephanie DeStefano, Josefine Dobbertin-Welsch, Daniel Walter, Bianca Schaub, Christina Schorlemer, Jana Kristin Eckert, Kathrin Zeber, Michael Kabesch, Ines Gellhaus, Gesine Hansen, Sabine Schnadt, Kathrin Urner, Julia Kahle, Simone Kreimeier
Rok vydání: 2021
Předmět:
Zdroj: Pediatr. Allergy Immunol. 33:e13652 (2022)
ISSN: 1399-3038
Popis: Allergic diseases, including atopic dermatitis (AD), food allergy (FA), asthma and allergic rhinitis/rhinoconjunctivitis (AR) are the most prevalent chronic childhood diseases affecting one in four children in the Western world (1). This global health problem imposes a significant burden on patient's quality of life (2), family, health care and society. The current state of knowledge assumes that complex interactions between genetic and environmental factors influence a child´s immune maturation prior to the development of allergic diseases (3). To date, no reliable predictions of allergy development exists. Current scores, including clinical features and laboratory data, have only reached limited specificity and/or sensitivity (4).
Databáze: OpenAIRE