Patient Education Programs in Pediatric Atopic Dermatitis: A Systematic Review of Randomized Controlled Trials and Meta-Analysis

Autor: Yuan Liang, Lin Ma, Chunping Shen, Mutong Zhao, Xiuhua Ma, Ying Wang
Rok vydání: 2020
Předmět:
Zdroj: Dermatology and Therapy, Vol 10, Iss 3, Pp 449-464 (2020)
Dermatology and Therapy
ISSN: 2190-9172
2193-8210
DOI: 10.1007/s13555-020-00365-z
Popis: Introduction Patient education is crucial for improving disease outcomes in atopic dermatitis (AD). This review aims to summarize evidence about the effectiveness of educational programs for parents of pediatric AD patients. Methods PubMed and Embase (inception to Feb 2020) were searched and randomized controlled trials (RCTs) in English were included. Risk of bias was assessed using Cochrane risk of bias tools and quality of evidence was assessed by Grading of Recommendations Assessment, Development and Evaluation (GRADE). Pooled standardized mean difference (SMD) and 95% confidence intervals (CIs) were calculated for the disease severity instrument (Scoring of Atopic Dermatitis, SCORAD) and quality of life (QoL) instruments using the random-effects model. Results A total of 13 RCTs were included in the systematic review. The meta-analysis of SCORAD contained seven studies with a total of 1853 patients. The reduction in disease severity (SCORAD) was larger in the treatment group (SMD = − 8.22, 95% CI = − 11.29, − 5.15; P
Databáze: OpenAIRE
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