The relationship between environmental exposures and hormonal abnormalities in pregnant women: An epidemiological study in Yazd, Iran
| Autor: | Mahmoud Taghavi, Sodeh Andishmand, Masomeh Khatbasreh, Sahar Ghale Askari, Samira Shahrokhi, Mohammad Hassan Sheikhha, Mohammad Hassan Ehrampoush, Hadi Eslami |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Down syndrome Iran Congenital Abnormalities Young Adult 03 medical and health sciences 0302 clinical medicine Pregnancy Risk Factors Environmental health Food Preserved Maternity and Midwifery Epidemiology medicine Humans Inhibins Pesticides Young adult Gynecology 030219 obstetrics & reproductive medicine business.industry Obstetrics and Gynecology Environmental exposure medicine.disease Epidemiologic Studies 030104 developmental biology Maternal Exposure Prenatal Exposure Delayed Effects Female Analysis of variance business Environmental Monitoring Environmental epidemiology Hormone |
| Zdroj: | Women and Birth. 31:e204-e209 |
| ISSN: | 1871-5192 |
| DOI: | 10.1016/j.wombi.2017.09.002 |
| Popis: | Problem The process of industrialization and lifestyle changes have gradually exposed human societies to a larger number of environmental risk factors, which may cause hormonal abnormalities and congenital anomalies. Background The current study aimed to investigate the relationship between environmental factors and hormonal abnormalities among pregnant women in Yazd, Iran. Methods A hundred participants were randomly selected from among a group of pregnant women. According to the screening tests (AFP, free β-HCG, uE3, PAPP-A, and inhibin-A) performed at the genome clinic in Yazd in 2016, the risk of Down Syndrome (DS) was sufficiently high in this group of pregnant women from which the participants were selected. A questionnaire was used to collect data on the degree of the participants’ exposure to pesticides at home, use of canned and fast foods, and consumption of greenhouse fruits. The collected data were analyzed by One-way ANOVA and Kruskal–Wallis Test. Findings The mean of Multiple of Median (MoM) for inhibin-A was significantly higher among pregnant women who often or always used pesticides at home (p = 0.047). The mean MoM for free β-HCG was significantly higher among pregnant women who often or always used canned foods (p = 0.024). Finally, the mean MoM for uE3 (1.85 ± 1.30) was significantly higher among pregnant women who never consumed greenhouse fruits (p = 0.003). Conclusion It can be concluded that it is possible to reduce environmental exposures affecting hormonal abnormalities among pregnant women by improving nutritional patterns, minimizing the use of pesticides at home, and reducing the intake of canned foods and greenhouse fruits. |
| Databáze: | OpenAIRE |
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