Subcritical Water Extraction of Epigallocatechin Gallate from Camellia sinensis and Optimization Study Using Response Surface Methodology
| Autor: | Dang Tuan Anh, Vu Thi Huong Anh, Do Quang Thai, Hoang Thanh Duong, Nguyen Minh Khoi, Nguyen Hoai Nguyen, Nguyen Tuan Hiep, Do Thi Thuy Linh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Bioengineering
Epigallocatechin gallate lcsh:Chemical technology 01 natural sciences complex mixtures lcsh:Chemistry response surface methodology chemistry.chemical_compound 0404 agricultural biotechnology subcritical water extraction Chemical Engineering (miscellaneous) Camellia sinensis lcsh:TP1-1185 Response surface methodology Chromatography Process Chemistry and Technology 010401 analytical chemistry Industrial scale Extraction (chemistry) food and beverages Water extraction modeling 04 agricultural and veterinary sciences 040401 food science 0104 chemical sciences Solvent chemistry lcsh:QD1-999 Yield (chemistry) |
| Zdroj: | Processes Volume 8 Issue 9 Processes, Vol 8, Iss 1028, p 1028 (2020) |
| ISSN: | 2227-9717 |
| DOI: | 10.3390/pr8091028 |
| Popis: | Background: Camellia sinensis is a plant whose leaves and buds are used to produce tea. With many medicinal activities already found, green tea has been consumed widely in the world. Methods: The subcritical water extraction (SWE) of epigallocatechin gallate (EGCG) from green tea leaves and the effect of the different extraction conditions are investigated by response surface methodology (RSM). Furthermore, the model of the extraction processes is reviewed for application at the industrial scale. Results: Based on the RSM data, the maximum yield of extraction is determined via optimizing different parameters of the extraction processes. Optimal conditions are as follows: extraction time of 6 min, extraction temperature at 120 ° C, and a sample/solvent ratio of 1:40 g/mL. Under such conditions, the best yield of EGCG is 4.665%. Moreover, the model of the extraction processes, which can be utilized for industry scale purpose, indicates a good correlation with the experimental data. Conclusions: Overall, SWE is competent and environmental-friendly, and it is also a highly selective and fast method. SWE is a promising method to take the place of organic solvents used in the extraction of weak polar and even non-polar natural compounds. Further studies on the scale-up of the extraction processes are ongoing. |
| Databáze: | OpenAIRE |
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