The Effects of Anti-Adhesion Materials in Preventing Postoperative Adhesion in Abdominal Cavity (Anti-Adhesion Materials for Postoperative Adhesions)
| Autor: | Fatih Mehmet Avşar, Murat Çakir, Tevfik Küçükkartallar, Mehmet Aköz, Ahmet Tekin, Mustafa Sahin |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Immunology Pharmacology toxicology Anti-Inflammatory Agents Biocompatible Materials Chitin Tissue Adhesions Abdominal cavity Peritoneal Diseases Methylprednisolone Severity of Illness Index Postoperative Complications Animals Immunology and Allergy Medicine Hyaluronic Acid Rats Wistar Anti adhesion Wound Healing Tissue Adhesion business.industry Abdominal Cavity Membranes Artificial Postoperative adhesion Rats Surgery Disease Models Animal medicine.anatomical_structure Carboxymethylcellulose Sodium Female business |
| Zdroj: | Inflammation. 30:244-249 |
| ISSN: | 1573-2576 0360-3997 |
| DOI: | 10.1007/s10753-007-9043-1 |
| Popis: | The purpose of this study was to compare the effects of anti-adhesion materials in postoperative adhesions.Rats were assigned to five groups: Group 1: Control. Group 2: chitin layers were used. Group 3: Na-hyaluronate / carboxymethylcellulose layers were used. Group 4: Na-hyaluronate gel was poured into the abdomen. Group 5: methylprednisolone was injected. The adhesion frequency and grade were scored according to Granat. Blood was taken for Hb, AST, BUN and albumin levels determination.The adhesion frequencies (right and left) and grades were as follow in Groups; I: 82%, 91%, 2.63 +/- 1.22; II: 8.3%, 25%, 0.58 +/- 0.66; III: 17%, 33%, 1.08 +/- 1.08; IV: 50%, 58%, 1.41 +/- 1.44; V: 50%, 42%, 1.41 +/- 1.50. The adhesion phase in all study groups was found significantly low compared to control group, p0.05. No difference was observed among serologic and hematological parameters in all groups.All the materials used significantly lowered the adhesion frequency and grade. |
| Databáze: | OpenAIRE |
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