Tracheoesophageal anastomosis, continent gastrostomy and oesophagostomy-a new experimental model in minipiglets
Autor: | E. Unsü, L. Ruprecht, Klaus Schaarschmidt, G.H. Willital, K. W. Paschertz, U. Stratmann |
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Rok vydání: | 1995 |
Předmět: |
Male
Esophagostomy medicine.medical_specialty Oesophagostomy Swine medicine.medical_treatment Tracheoesophageal fistula Aspiration pneumonia Anastomosis Enteral Nutrition Esophagus Animals Laboratory Occlusion medicine Animals Esophageal Atresia Gastrostomy General Veterinary business.industry Anastomosis Surgical Body Weight medicine.disease Diet Surgery Trachea Disease Models Animal medicine.anatomical_structure Swine Miniature Animal Science and Zoology business Tracheoesophageal Fistula |
Zdroj: | Laboratory Animals. 29:411-419 |
ISSN: | 1758-1117 0023-6772 |
DOI: | 10.1258/002367795780740131 |
Popis: | Tracheoesophageal fistulae endanger newborn children by aspiration pneumonia. An animal model of this dangerous malformation was thought to be impossible until now. By tracheoesophageal anastomosis, occlusion of the oesophagogastral junction, proximal cervical oesophagostomy and continent gastrostomy in 25 minipiglets a reliable model of tracheoesophageal fistula has been developed. After establishing the model in a pilot study the mortality following the establishment of this procedure was 5.6% and the minipiglets survived in excellent condition for 2-10 week periods under complete alimentary restriction and gastrostomy feeding. Therefore the method seems to be suitable for long-term investigations on major oesophagotracheal surgery. |
Databáze: | OpenAIRE |
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