Phytochemical Study of Stem and Leaf of Clausena lansium
| Autor: | Zhong-Hua Xiong, Wenwen Peng, Yu-Yan Li, Fang Zhang, Xugen Shi, Bao-Tong Li, Xiao-Xiang Fu, Guanghua Huo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Clausena lansium
Pharmaceutical Science sesquiterpene glycosides Sesquiterpene Stem-and-leaf display 01 natural sciences Analytical Chemistry lcsh:QD241-441 chemistry.chemical_compound lcsh:Organic chemistry Clausena aromatic glycosides Drug Discovery Lansium Physical and Theoretical Chemistry chemistry.chemical_classification biology Traditional medicine 010405 organic chemistry Organic Chemistry Glycoside biology.organism_classification 0104 chemical sciences 010404 medicinal & biomolecular chemistry Rutaceae dihydrofuranocoumarin glycosides chemistry Phytochemical Chemistry (miscellaneous) Molecular Medicine |
| Zdroj: | Molecules Volume 24 Issue 17 Molecules, Vol 24, Iss 17, p 3124 (2019) |
| ISSN: | 1420-3049 |
| DOI: | 10.3390/molecules24173124 |
| Popis: | Clausena lansium Lour. Skeels (Rutaceae) is widely distributed in South China and has historically been used as a traditional medicine in local healthcare systems. Although the characteristic components (carbazole alkaloids and coumarins) of C. lansium have been found to possess a wide variety of biological activities, little attention has been paid toward the other components of this plant. In the current study, phytochemical analysis of isolates from a water-soluble stem and leaf extract of C. lansium led to the identification of 12 compounds, including five aromatic glycosides, four sesquiterpene glycosides, two dihydrofuranocoumarin glycosides, and one adenosine. All compounds were isolated for the first time from the genus Clausena, including a new aromatic glycoside (1), a new dihydrofuranocoumarin glycoside (6), and two new sesquiterpene glycosides (8 and 9). The phytochemical structures of the isolates were elucidated using spectroscopic analyses including NMR and MS. The existence of these compounds demonstrates the taxonomic significance of C. lansium in the genus Clausena and suggests that some glycosides from this plant probably play a role in the anticancer activity of C. lansium to some extent. |
| Databáze: | OpenAIRE |
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