Broad spectrum antimicrobial activity of Ca(Zn(OH)3)2·2H2O and ZnO nanoparticles synthesized by the sol–gel method
| Autor: | M. Soria-Castro, Patricia Quintana, Aránzazu Sierra-Fernández, S. C. De la Rosa-García, S. Gómez-Cornelio, N. Gómez-Ortíz |
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| Přispěvatelé: | Consejo Nacional de Ciencia y Tecnología (México), De la Rosa-García, S. C. [0000-0002-6654-4532], De la Rosa-García, S. C. |
| Rok vydání: | 2019 |
| Předmět: |
Materials science
chemistry.chemical_element Nanoparticle 02 engineering and technology Zinc Calcium 010402 general chemistry 01 natural sciences Biomaterials chemistry.chemical_compound Zinc hydroxide Materials Chemistry MIC Sol-gel Agar-well diffusion method General Chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Antimicrobial 0104 chemical sciences Electronic Optical and Magnetic Materials Antimicrobial properties Biodeterioration chemistry Ca(Zn(OH)3)2·2H2O and ZnO NPs Ceramics and Composites Degradation (geology) 0210 nano-technology Antibacterial activity Structural damage Nuclear chemistry |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | The process of biodeterioration is one of the main problems affecting historical monuments and buildings. On rock surfaces, different types of microorganisms establish in the most adequate niches and accelerate degradation, leading to the irreversible loss of cultural heritage. Therefore, new ways to preserve cultural heritage must be urgently studied to prevent such damage. In this study, the broad-spectrum antimicrobial activity of calcium zinc hydroxide dehydrate [Ca(Zn(OH)3)2·2H2O] (CZ) and zinc oxide (ZnO) nanoparticles synthesized by the sol–gel method is examined against fungal and bacterial model organisms. The selected microbes were inhibited by both nanoparticles, yet CZ was the most effective, with a bactericidal activity of 1.25 to 5 mg/mL and a fungicidal activity of 0.625 mg/mL. Both nanoparticles caused structural damage to the evaluated fungal cells, resulting in morphological changes and affecting the germination of conidia. For the first time in the literature, the antibacterial activity and the mode of action of CZ are reported. In conclusion, CZ nanoparticles are shown to be potential candidates for the treatment of rock surfaces of built cultural heritage. We are grateful for the financial support of the National Council for Science and Technology (Consejo Nacional de Ciencia y Tecnología [CONACyT]) of the “Fronteras de la Ciencia 138” project. Additional thanks are extended to CONACyT for the doctoral scholarship granted to MSC 282192. |
| Databáze: | OpenAIRE |
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