Management of isolated retroperitoneal Castelman’s disease: A case report
| Autor: | Zoghlami Ayoub, Rebii Sabeur, Hakim Zenaidi, Ben Ismail Imen, Yahmadi Abdelwahed |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Exploratory laparotomy medicine.medical_treatment Lymphoproliferative disorders Angiofollicular Lymphoid Hyperplasia Disease Lymphoid hyperplasia Article 03 medical and health sciences 0302 clinical medicine Unicentric medicine Hyaline business.industry Mediastinum medicine.disease medicine.anatomical_structure Angiofollicular lymphoid hyperplasia 030220 oncology & carcinogenesis Etiology Surgical management 030211 gastroenterology & hepatology Surgery Castelman disease Radiology medicine.symptom business Retroperitoneal tumor |
| Zdroj: | International Journal of Surgery Case Reports |
| ISSN: | 2210-2612 |
| Popis: | Highlights • The unicentric form of Castelman's disease (CD) is rarely present as an isolated retroperitoneal tumor. • Because of its rarity even experienced surgeons may misdiagnose retroperitoneal CD. • Surgeons should consider this disease because surgical resection is the only treatment of the unicentric form. Introduction Castleman’s disease (CD) is a rare disorder characterized by benign angio follicular lymphoid hyperplasia, with gentle behavior. Its etiology and prevalence are unclear. It is usually found in the mediastinal area and it is rare to see this tumor in the retroperitoneum. Presentation of case A 53 year old male with a retroperitoneal hypervascular calcified mass densely adherent to the psoas muscle that was accidentally encountered on a CT scan. Provisional diagnosis of retroperitoneal liposarcoma was made and the patient underwent an exploratory laparotomy. The histologic examination of the surgically resected specimen disclosed « a hyaline type of Castleman’s disease ». Discussion Castleman’s disease, is a rare heterogenous group of lymphoproliferative disorders that arises mostly in the mediastinum. The retroperitoneal localization is very rare. Clinically, CD can be subdivided into a localized form (unicentric disease) and a generalized form (multicentric disease) according to the number of lymph nodes involved. A careful histological and immunohistochemical examination of the tumor tissue after surgery is the only way for tumor diagnosis. Conclusion Castelman’s disease is a rare entity that has often benign and non invasive behavior, but remains a diagnostic challenge. There is no reliable diagnostic method and its definitive diagnosis is based on histopathology report. For treating the unicentric variant, radical surgical resection is considered to be the gold standard. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|