Aventriculi associated with holoprosencephaly in a dog
| Autor: | Laura M. Lee, Lauren Blume, Starr Cameron, Laura Barnard, Alexane Durand |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
040301 veterinary sciences 610 Medicine & health Case Report Case Reports 030204 cardiovascular system & hematology Ventricular system 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Holoprosencephaly Magnetic resonance imaging of the brain medicine neuropathology ventriculogram Third ventricle General Veterinary medicine.diagnostic_test business.industry ventricles congenital 04 agricultural and veterinary sciences Anatomy Lobar holoprosencephaly medicine.disease malformation medicine.anatomical_structure Neurology Atresia 590 Animals (Zoology) Histopathology Choroid plexus SMALL ANIMAL business |
| Zdroj: | Journal of Veterinary Internal Medicine Barnard, Laura; Durand, Alexane; Blume, Lauren; Lee, Laura; Cameron, Starr (2020). Aventriculi associated with holoprosencephaly in a dog. Journal of veterinary internal medicine, 34(6), pp. 2682-2686. Wiley-Blackwell 10.1111/jvim.15907 |
| ISSN: | 1939-1676 0891-6640 |
| DOI: | 10.1111/jvim.15907 |
| Popis: | Case Description A 10‐month‐old neutered male mixed breed dog was presented for assessment of poorly controlled seizures. Clinical Findings Magnetic resonance imaging of the brain disclosed complete absence of the lateral and third ventricles and mesencephalic aqueduct. Postmortem computed tomographic (CT) imaging and positive contrast cisterno‐ventriculography confirmed the lack of a contiguous ventricular system. However, histopathology identified the presence of vestigial lateral and third ventricles with hypoplastic choroid plexus, atresia of the third ventricle, and fused thalami, consistent with a diagnosis of lobar holoprosencephaly (HPE). Clinical Relevance To our knowledge, this report is the first case of radiographically confirmed aventriculi associated with HPE, a rare congenital malformation previously reported in people, to be described in veterinary medicine. |
| Databáze: | OpenAIRE |
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