Antibody removal and subsequent transplantation of a highly sensitised paediatric renal patient
| Autor: | Robert Vaughan, D. J. Bevan, Bruce M. Hendry, C K Lea, C. G. Koffman, S P Rigden, M. Bewick, B S Carey, Robert Higgins |
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| Rok vydání: | 1996 |
| Předmět: |
Nephrology
Graft Rejection Male medicine.medical_specialty HLA Antigens Renal Dialysis Internal medicine medicine Humans Immunoadsorption Child Kidney transplantation Autoantibodies Transplantation Kidney Hematology biology business.industry Autoantibody medicine.disease Kidney Transplantation Surgery medicine.anatomical_structure biology.protein Antibody business Immunosorbents |
| Zdroj: | Transplant international : official journal of the European Society for Organ Transplantation. 9(2) |
| ISSN: | 0934-0874 |
| Popis: | We report a successful renal transplant in a highly sensitised paediatric recipient following removal of HLA-specific antibodies by extracorporeal immunoadsorption. The immediate pretransplant cytotoxic titre against the donor was greater than 1:512; this was reduced to negativity by two immunoadsorption sessions prior to transplant surgery. We also describe the presence of unexpected non-HLA-specific antibody activities in this immunoadsorbed patient. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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