Radiotherapy for the treatment of pituitary adenomas: A dosimetric comparison of three planning techniques
| Autor: | Johnatan Rubalcava-Ortega, Rubí Ramos-Prudencio, Ricardo Iván Balderrama-Ibarra, José Alfredo Herrera-González, Sandra Ileana Pérez-Álvarez, Mayra Angélica de León-Alfaro, Christian Haydée Flores-Balcazar, Jonathan Elizalde-Cabrera, Lissett Espinoza-Alvarado |
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| Rok vydání: | 2020 |
| Předmět: |
business.industry
medicine.medical_treatment Planning target volume medicine.disease Volumetric modulated arc therapy 030218 nuclear medicine & medical imaging Radiation therapy Conformity index 03 medical and health sciences 0302 clinical medicine Oncology Pituitary adenoma 030220 oncology & carcinogenesis medicine Neck flexion Radiology Nuclear Medicine and imaging Original Research Article Treatment time Radiation treatment planning business Nuclear medicine |
| Zdroj: | Rep Pract Oncol Radiother |
| ISSN: | 1507-1367 |
| DOI: | 10.1016/j.rpor.2020.04.020 |
| Popis: | AIM: Our goal was to compare conformal 3D (C3D) radiotherapy (RT), modulated intensity RT (IMRT), and volumetric modulated arc therapy (VMAT) planning techniques in treating pituitary adenomas. BACKGROUND: RT is important for managing pituitary adenomas. Treatment planning advances allow for higher radiation dosing with less risk of affecting organs at risk (OAR). MATERIALS AND METHODS: We conducted a 5-year retrospective review of patients with pituitary adenoma treated with external beam radiation therapy (C3D with flattening filter, flattening filter-free [FFF], IMRT, and VMAT). We compared dose-volume histogram data. For OARs, we recorded D2%, maximum, and mean doses. For planning target volume (PTV), we registered V95%, V107%, D95%, D98%, D50%, D2%, minimum dose, conformity index (CI), and homogeneity index (HI). RESULTS: Fifty-eight patients with pituitary adenoma were included. Target-volume coverage was acceptable for all techniques. The HI values were 0.06, IMRT; 0.07, VMAT; 0.08, C3D; and 0.09, C3D FFF (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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