Quadruple Valve Replacement for Carcinoid Heart Disease

Autor: Syed Saleem Mujtaba, Stephen Clark
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Brazilian Journal of Cardiovascular Surgery, Volume: 33, Issue: 4, Pages: 398-403, Published: AUG 2018
Brazilian Journal of Cardiovascular Surgery, Vol 33, Iss 4, Pp 398-403
Brazilian Journal of Cardiovascular Surgery
Brazilian Journal of Cardiovascular Surgery v.33 n.4 2018
Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)
instacron:SBCCV
ISSN: 1678-9741
Popis: Introduction: Carcinoid heart disease most frequently involves the tricuspid or, more rarely, the pulmonary valve and presents with right heart failure as 5-HT is metabolized by the lung. Left-sided valve involvement is quite rare. We describe our experience of 3 patients presenting with heart failure secondary to carcinoid heart disease affecting all four cardiac valves. There are only four previous isolated case reports in the literature.\ud \ud Methods: All three patients underwent quadruple valve replacement during a single operation. Right ventricular outflow tract reconstruction with a pericardial patch was performed in all patients. For 24 hours prior to surgery, all patients received intravenous octreotide, which continued in intensive care for at least 24 hours.\ud \ud Results: Mean cross-clamp and bypass times were 175 (range 164-197 minutes) and 210 (range 195-229 minutes) minutes, respectively. Mean intensive treatment unit (ITU) and inpatient stays were 2.3 (range 2-3 days) and 12 (range 9-16 days) days, respectively. One patient was reopened for bleeding 4 hours postoperatively from a ventricular pacing wire site. None required a permanent pacemaker postoperatively. There were no other complications in any patient. The quality of life was excellent at 6-16 months clinic follow-up as they were in NYHA 1. Postoperative echocardiography showed no paravalvular leaks and well-functioning prostheses in all cases.\ud \ud Conclusion: Surgery to replace all four valves is feasible with excellent medium-term survival and a very low rate of complications. Patients with carcinoid heart disease should always be considered for surgery irrespective of the extent of valvular involvement.
Databáze: OpenAIRE