Modulatory Effects of Plant Polyphenols on Bone Remodeling: A Prospective View From the Bench to Bedside
| Autor: | Stefania Lucia Nori, Federico Berton, Fulvia Costantinides, Roberto Di Lenarda, Nunziatina De Tommasi, Vanessa Nicolin |
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| Přispěvatelé: | Nicolin, Vanessa, De Tommasi, Nunziatina, Lucia Nori, Stefania, Costantinides, Fulvia, Berton, Federico, DI LENARDA, Roberto |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
musculoskeletal diseases Endocrinology Diabetes and Metabolism Osteoporosis 030209 endocrinology & metabolism Review biomolecules polyflavonoids bone remodeling titanium implant coating surfaces lcsh:Diseases of the endocrine glands. Clinical endocrinology biomolecules Bone resorption polyflavonoid Bone remodeling 03 medical and health sciences bone remodeling coating surfaces polyflavonoids titanium implant 0302 clinical medicine Endocrinology Periodontal disease Osteoclast medicine lcsh:RC648-665 business.industry Bone metastasis coating surface medicine.disease Bench to bedside biomolecule 030104 developmental biology medicine.anatomical_structure Rheumatoid arthritis Cancer research business |
| Zdroj: | Frontiers in Endocrinology Frontiers in Endocrinology, Vol 10 (2019) |
| Popis: | During the past, a more comprehensive knowledge of mechanisms implicated in bone resorption processes has driven researchers to develop a compound library of many small molecules that specifically interfere with the genesis of osteoclast precursors cells. Natural compounds that suppress osteoclast commitment may have therapeutic value in treating pathologies associated with bone resorption like osteoporosis, rheumatoid arthritis, bone metastasis, and periodontal disease. The present review is focused on the current knowledge on the polyphenols derived from plants that could be efficacious in suppressing osteoclast differentiation and bone resorption. |
| Databáze: | OpenAIRE |
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