Maternal education and offspring birth weight for gestational age: the mediating effect of smoking during pregnancy
| Autor: | Morgane Ballon, Marie-Aline Charles, Laura Pryor, Maria Melchior, Aurélie Nakamura, Fabienne Lesueur, Barbara Heude, Sandrine Lioret |
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| Přispěvatelé: | Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), École des Hautes Études en Santé Publique [EHESP] (EHESP), Johns Hopkins Bloomberg School of Public Health [Baltimore], Johns Hopkins University (JHU), Equipe 6 : ORCHAD - Origines précoces de la santé du développement de l'enfant (CRESS - U1153), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut Convergences Migrations [Aubervilliers] (IC Migrations) |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Offspring Birth weight Birthweight Gestational Age Cohort Studies 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics Tobacco Smoking Birth Weight Humans Medicine 030212 general & internal medicine mediation analysis Child 2. Zero hunger business.industry Obstetrics Smoking Infant Newborn Public Health Environmental and Occupational Health Gestational age health inequalities medicine.disease Infant mortality educational attainment Infant Small for Gestational Age Small for gestational age Female Underweight medicine.symptom business Body mass index [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| Zdroj: | European Journal of Public Health European Journal of Public Health, Oxford University Press (OUP): Policy B-Oxford Open Option D, 2020, 30 (5), pp.1001-1006. ⟨10.1093/eurpub/ckaa076⟩ |
| ISSN: | 1464-360X 1101-1262 |
| DOI: | 10.1093/eurpub/ckaa076 |
| Popis: | Background Small for gestational age (SGA) birth weight, a risk factor for infant mortality and delayed child development, is associated with maternal educational attainment. Maternal tobacco smoking during pregnancy could contribute to this association. We aimed to quantify the contribution of maternal smoking during pregnancy to social inequalities in child birth weight for gestational age (GA). Methods Data come from the French nation-wide ELFE cohort study, which included 17 155 singletons. Birth weights for GA were calculated using z-scores. Associations between maternal educational attainment, tobacco smoking during pregnancy and child birth weight for GA were ascertained using mediation analysis. Mediation analyses were also stratified by maternal pre-pregnancy body mass index. Results Low maternal educational attainment was associated with an increased odd of tobacco smoking during pregnancy [adjusted OR (ORa) = 2.58 (95% CI 2.34–2.84)] as well as a decrease in child birth weight for GA [RRa = 0.94 (95% CI 0.91–0.98)]. Tobacco smoking during pregnancy was associated with a decrease in offspring birth weight for GA [RRa = 0.73 (95% CI 0.70–0.76)]. Mediation analysis suggests that 39% of the effect of low maternal educational attainment on offspring birth weight for GA was mediated by smoking during pregnancy. A more important direct effect of maternal educational attainment on child birth weight for GA was observed among underweight women [RRa = 0.82 (95% CI 0.72–0.93)]. Conclusions The relationship between maternal educational attainment and child birth weight for GA is strongly mediated by smoking during pregnancy. Reducing maternal smoking could lessen the occurrence of infant SGA and decrease socioeconomic inequalities in birth weight for GA. |
| Databáze: | OpenAIRE |
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