Improvement in diagnosis of metastatic pituitary carcinoma by 68Ga DOTATATE PET/CT
| Autor: | Jianqi Xiao, Renzhi Wang, Dingrong Zhong, Wenbin Ma, Zhaohui Zhu |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Multimodal Imaging Biopsy medicine Organometallic Compounds Humans Radiology Nuclear Medicine and imaging Pituitary Neoplasms PET-CT medicine.diagnostic_test Somatostatin receptor business.industry Brain Neoplasms Pituitary tumors Carcinoma General Medicine Middle Aged medicine.disease Cerebellopontine angle Somatostatin Positron-Emission Tomography Radionuclide therapy Pituitary carcinoma Female Radiology Radiopharmaceuticals business Tomography X-Ray Computed |
| Zdroj: | Clinical nuclear medicine. 40(2) |
| ISSN: | 1536-0229 |
| Popis: | Pituitary carcinoma is a rare disease with a challenge in both diagnosis and treatment. A 50-year-old female patient who underwent transsphenoidal resection of a pituitary tumor experienced progressive headache. For the evaluation, Ga DOTATATE PET/CT was used and compared with F-FDG PET/CT and enhanced MRI. Multiple lesions were detected by Ga DOTATATE PET/CT at the cerebral cortex, cerebellum, and cerebellopontine angle with a higher contrast than F-FDG PET/CT and enhanced MRI. With a biopsy, the patient was diagnosed as metastatic pituitary carcinoma. Moreover, it thus presents potential therapeutic implications on molecular-targeted therapy using somatostatin analogs and peptide receptor radionuclide therapy targeting the somatostatin receptors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|