Prevalence and Prescription of Antidepressants in Depression with Somatic Comorbidity in Asia
| Autor: | Eun Kee Chung, Ee Heok Kua, Pichet Udomratn, Chuanyue Wang, Kang Sim, Jitendra K. Trivedi, Naotaka Shinfuku, Tian-Mei Si, Yanling He, Norman Sartorius, Yu-Tao Xiang, Chao Chen, Kok Yoon Chee, Senta Fujii, Chay Hoon Tan, Gabor S. Ungvari |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Asia lcsh:Medicine Disease Drug Prescriptions Noradrenergic and specific serotonergic antidepressant Prescription Asian People Internal medicine Diabetes mellitus Prevalence medicine Humans Medical prescription Psychiatry Depression (differential diagnoses) Somatic Comorbidity Depression business.industry Incidence (epidemiology) lcsh:R General Medicine Middle Aged medicine.disease Comorbidity Antidepressive Agents Psychotropic drug Female Original Article business |
| Zdroj: | Chinese Medical Journal, Vol 128, Iss 7, Pp 853-858 (2015) Chinese Medical Journal |
| ISSN: | 0366-6999 |
| DOI: | 10.4103/0366-6999.154272 |
| Popis: | Background: Depression is often comorbid with chronic somatic diseases. Few previous studies have investigated the prevalence of somatic diseases in depression or the prescription pattern of antidepressants in comorbidly depressed patients in Asia. This study aimed to investigate the prevalence of somatic comorbidity (SC) in depression and compared the prescriptions of antidepressants in depressed patients with and without SC. Methods: A total of 2320 patients treated with antidepressants in 8 Asian countries were examined, and a diagnosis was based on the International Classification of Disease, 10 th revision. We listed 17 common chronic somatic diseases. Patients' socio-demographic and clinical characteristics and psychotropic drug prescriptions were recorded using a standardized protocol and data collection procedure. Results: Of the patients examined, 1240 were diagnosed with depression and 30% of them ( n = 375) had SC. The most common comorbid condition was diabetes (23.7%). The patients with SC were more likely to seek help at a general hospital (74.7% vs. 47.2%), and had a higher incidence of symptoms involving sadness, disturbed sleep, and poor appetite. Noradrenergic and specific serotonergic antidepressant was prescribed more for patients with SC than for those without SC (30.4% vs. 22.9%). Conclusions: SC is common in depressed Asian patients. It is important to strengthen the recognition of depression, especially in general hospitals and when patients report some somatic discomfort. It is also a matter of urgency to establish evidence-based guidelines for the use of new antidepressants in depressed patients with SC. |
| Databáze: | OpenAIRE |
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