Two new isoaurones derivatives from Callistephus chinensis flower
| Autor: | Guo-hui Shi, Xiaoshu Zhang, Yuqing Zhao, Zhen-ting Liu, Jiaqing Cao, Jing-xin Liu |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Callistephus chinensis China Magnetic Resonance Spectroscopy Stereochemistry Plant Science Flowers Asteraceae 01 natural sciences Biochemistry Analytical Chemistry 03 medical and health sciences Inhibitory Concentration 50 Cell Line Tumor Humans Benzofurans biology Molecular Structure 010405 organic chemistry 030111 toxicology Organic Chemistry biology.organism_classification 0104 chemical sciences Phytochemical Drug Screening Assays Antitumor Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | Natural product research. 30(3) |
| ISSN: | 1478-6427 |
| Popis: | Two new isoaurones derivatives were obtained from Callistephus chinensis flower. Their structures were elucidated on the basis of extensive spectroscopic analyses. Both of the new compounds were evaluated cytotoxic activity. Phytochemical investigation of Callistephus chinensis flower led to the isolation of two new isoaurones derivatives (Z)-4′,4,10-trihydroxy-siamaurone (1) and (E)-4′,4,10-trihydroxy-siamaurone (2). The structures of these new compounds were identified by the interpretation of spectroscopic data (mainly 1D and 2D NMR) and by comparison with data reported in the literature. Both of the new compounds were evaluated for their cytotoxicity. |
| Databáze: | OpenAIRE |
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