Acrometastases to the Hand: A Systematic Review
| Autor: | Gianluca Scalia, Francesca Graziano, Giacomo Cuttone, Maurizio Passanisi, Valerio Da Ros, Gerardo Iacopino, Santino Ottavio Tomasi, Giuseppe Emmanuele Umana, Lidia Strigari, Massimo Ippolito, Antonino Germanò, Fabio Barone, Salvatore Cicero, Maria Gabriella Sabini, Paolo Palmisciano, Giuseppe Roberto Giammalva, Giovanni Federico Nicoletti, Gianluca Pompili, I.V. Patti, Paolo Amico, Giovanni Raffa, Stefania Mele, Rosario Maugeri |
|---|---|
| Přispěvatelé: | Umana G.E., Scalia G., Palmisciano P., Passanisi M., Da Ros V., Pompili G., Barone F., Amico P., Tomasi S.O., Graziano F., Patti I.V., Mele S., Maugeri R., Raffa G., Giammalva G.R., Iacopino D., Germano A., Nicoletti G.F., Ippolito M., Sabini M.G., Cicero S., Strigari L., Cuttone G. |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Medicine (General) medicine.medical_specialty Lung Neoplasms Adolescent medicine.medical_treatment Bone Neoplasms Wrist Metastasis Fingers Young Adult Finger Phalanges R5-920 Breast cancer Thumb metastases medicine Carcinoma Chemotherapy Humans Child Aged Aged 80 and over Radiotherapy Acrometastases business.industry Genitourinary system Incidence (epidemiology) Immunotherapy Female Middle Aged Prognosis General Medicine medicine.disease Primary tumor Radiation therapy medicine.anatomical_structure Systematic Review Radiology business |
| Zdroj: | Medicina, Vol 57, Iss 950, p 950 (2021) Medicina |
| ISSN: | 1648-9144 |
| Popis: | Background and Objectives: The term acrometastases (AM) refers to secondary lesions sited distally to the elbow and knee, representing 0.1% of all bony metastases. By frequency, pulmonary cancer and gastrointestinal and genitourinary tract neoplasms are the most responsible for the reported AM. Improvements in oncologic patient care favor an increase in the incidence of such rare cases. We performed a systematic review of acrometastases to the hand to provide further insight into the management of these fragile patients. We also present a peculiar case of simultaneous acrometastasis to the ring finger and pathological vertebral fracture. Material and Methods: A literature search according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement was conducted using the PubMed, Google Scholar, and Scopus databases in December 2020 on metastasis to the hand and wrist, from 1986 to 2020. MeSH terms included acrometastasis, carpal metastasis, hand metastasis, finger metastasis, phalangeal metastasis, and wrist metastasis. Results: In total, 215 studies reporting the follow-up of 247 patients were analyzed, with a median age of 62 years (range 10–91 years). Overall, 162 out of 247 patients were males (65.6%) and 85 were females (34.4%). The median reported follow-up was 5 months (range 0.5–39). The median time from primary tumor diagnosis to acrometastasis was 24 months (range 0.7–156). Acrometastases were located at the finger/phalanx (68.4%), carpal (14.2%), metacarpal (14.2%), or other sites (3.2%). The primary tumors were pulmonary in 91 patients (36.8%). The average interval from primary tumor diagnosis to acrometastasis varied according to the primary tumor type from 2 months (in patients with mesenchymal tumors) to 64.0 months (in patients with breast cancer). Conclusions: Acrometastases usually develop in the late stage of oncologic disease and are associated with short life expectancy. Their occurrence can no longer be considered rare; physicians should thus be updated on their surgical management and their impact on prognosis and survival. |
| Databáze: | OpenAIRE |
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