Comparison of Hip and Knee Arthroplasty Rates of Individuals With and Without Prader-Willi Syndrome
| Autor: | Harold J.P. van Bosse, Jessica B Cox, Marie G. Gantz, Kevin L. Ong |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male musculoskeletal diseases congenital hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty Adolescent Databases Factual Arthroplasty Replacement Hip medicine.medical_treatment Population MEDLINE Young Adult 03 medical and health sciences 0302 clinical medicine Prevalence Hip Dislocation Humans Medicine Orthopedics and Sports Medicine Young adult Arthroplasty Replacement Knee Child education Healthcare Cost and Utilization Project Hip dysplasia 030222 orthopedics education.field_of_study Inpatient care business.industry Infant Newborn Infant nutritional and metabolic diseases General Medicine Perioperative Length of Stay Middle Aged medicine.disease Arthroplasty Patient Discharge nervous system diseases Child Preschool Pediatrics Perinatology and Child Health Female business Prader-Willi Syndrome |
| Zdroj: | Journal of Pediatric Orthopaedics. 40:e362-e366 |
| ISSN: | 0271-6798 |
| DOI: | 10.1097/bpo.0000000000001490 |
| Popis: | BACKGROUND Prader-Willi syndrome (PWS) is a complex genetic condition, affecting between 1:10,000 and 1:30,000. The prevalence of hip dysplasia in children with PWS is reportedly between 8% and 30%, but the long-term consequences of residual hip dysplasia remain largely unknown in this population. The purpose of this study was to comparatively estimate the number of total hip arthroplasty (THA) and total knee arthroplasty (TKA) procedures performed on adults with and without PWS, using a national hospital discharge database, in an effort to elucidate long-term outcomes and guide clinicians treating orthopaedic concerns in younger individuals with PWS. METHODS The National Inpatient Sample of the Healthcare Cost and Utilization Project is the largest all-payer inpatient care database, containing annual data from >7 million hospital stays; sampling weights and stratification variables are provided for producing estimates of >35 million hospitalizations nationwide. THA and TKA procedures were identified, then stratified by whether or not the patient had a diagnosis of PWS. The ages of the 2 groups and sex mix were compared, as was the length of stay for the procedure, and discharge status. RESULTS From 2004 to 2014, 9.4 million patients nationwide, by weighted estimate, underwent THA (3.1 million) or TKA (6.3 million). Sixty-five patients were identified as having the diagnosis of PWS (39 with THA, 26 with TKA); 7 patients per million having hip or knee arthroplasties had PWS. Sixty-eight percent of those with PWS were younger than 50 years, compared with only 7% of those without PWS (P |
| Databáze: | OpenAIRE |
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