Similar adverse pregnancy outcome in native and nonnative dutch women with pregestational type 2 diabetes: a multicentre retrospective study
| Autor: | Manon C. J. Schreuder, Willy Visser, Marieke Hellinga, Marijke M. Faas, Rutgert Bianchi, Bart B. L. Groen, Wim J. Sluiter, Sharon Moerman, Anton K. M. Bartelink, Petronella H. L. M. Geelhoed-Duijvestijn, Gerard H. A. Visser, Paul P. van den Berg, Harold W. de Valk, Thera P. Links |
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| Přispěvatelé: | Damage and Repair in Cancer Development and Cancer Treatment (DARE), Reproductive Origins of Adult Health and Disease (ROAHD), Guided Treatment in Optimal Selected Cancer Patients (GUTS), Translational Immunology Groningen (TRIGR) |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | ISRN Obstetrics and Gynecology ISRN Obstetrics and Gynecology, 2013:361435 |
| ISSN: | 2090-4436 |
| Popis: | Objective. To assess the incidence of adverse pregnancy outcome in native and nonnative Dutch women with pregestational type 2 diabetes (T2D) in a multicenter study in The Netherlands. Methods. Maternal characteristics and pregnancy outcome were retrospectively reviewed and the influence of ethnicity on outcome was evaluated using independent t-test, Mann-Whitney U-test, and chi-square test. Results. 272 pregnant women (80 native and 192 non-native Dutch) with pregestational T2D were included. Overall outcome was unfavourable, with a perinatal mortality of 4.8%, major congenital malformations of 6.3%, preeclampsia of 11%, preterm birth of 19%, birth weight >90th percentile of 32%, and a Caesarean section rate of 42%. In nonnative Dutch women, the glycemic control was slightly poorer and the gestational age at booking somewhat later as compared to native Dutch women. However, there were no differences in incidence of preeclampsia/HELLP, preterm birth, perinatal mortality, macrosomia, and congenital malformations between those two groups. Conclusions. A high incidence of adverse pregnancy outcomes was found in women with pregestational T2D, although the outcome was comparable between native and non-native Dutch women. This suggests that easy access to and adequate participation in the local health care systems contribute to these comparable outcomes, offsetting potential disadvantages in the non-native group. |
| Databáze: | OpenAIRE |
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