Phylogenetic analysis of the rpoB gene from the plastid-like DNA of Plasmodium falciparum
| Autor: | Malcolm Strath, Robert J.M. Wilson, Malcolm J. Gardner, Nick Goldman, P. W. Moore, Donald H. Williamson, Kaveri Rangachari, Phillip Barnett, Andrea Whyte |
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| Přispěvatelé: | Other departments |
| Jazyk: | angličtina |
| Rok vydání: | 1994 |
| Předmět: |
Operon
Genes Protozoan Molecular Sequence Data Plasmodium falciparum Extrachromosomal Inheritance Genome Species Specificity Phylogenetics Extrachromosomal DNA parasitic diseases Animals Amino Acid Sequence Plastids Codon Molecular Biology Gene Phylogeny DNA Primers Genetics biology Base Sequence Sequence Homology Amino Acid fungi Nucleic acid sequence DNA-Directed RNA Polymerases DNA Protozoan rpoB biology.organism_classification bacteria Parasitology DNA Circular |
| Zdroj: | Molecular and biochemical parasitology, 66(2), 221-231. Elsevier |
| ISSN: | 0166-6851 |
| Popis: | Malaria and other Apicomplexan parasites harbour two extrachromosomal DNAs. One is mitochondrial and the other is a 35-kb circle with some plastid-like features but whose provenance and function is unknown. In addition to genes for rRNAs, tRNAs and ribosomal proteins, the 35-kb circular DNA of Plasmodium falciparum carries an rpoBC operon which encodes subunits of a eubacteria-like RNA polymerase. The phylogenetic analysis of the complete rpoB sequence presented here supports our inference that the 35-kb circle is the remnant of a plastid genome. |
| Databáze: | OpenAIRE |
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