Effect of Rourea coccinea on ethanol-induced male infertility in Wistar albino rats
| Autor: | Tossou Jacques Dougnon, Jean-Marc Atègbo, Tamègnon Victorien Dougnon, Eric Agbodjento, Jean Robert Klotoé, Téniola Isabelle Sacramento |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Urology 030232 urology & nephrology Physiology Positive control Male infertility 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Endocrinology Testis Medicine Animals Humans Testosterone Rats Wistar Infertility Male 030219 obstetrics & reproductive medicine Ethanol Sperm Count business.industry Plant Extracts General Medicine medicine.disease Reference drug Sperm Spermatozoa Rats Seminiferous tubule medicine.anatomical_structure chemistry Sperm Motility business Connaraceae Hormone |
| Zdroj: | AndrologiaREFERENCES. 53(6) |
| ISSN: | 1439-0272 |
| Popis: | Ethanol consumption is a risk factor of male infertility. The use of medicinal plants offers an alternative for the treatment of male infertility in developing countries. This study aimed to evaluate the Rourea coccinea effect on ethanol-induced male infertility in Wistar rats. Twenty-five (25) male Wistar rats were randomised into five groups of five rats and treated by oesophageal gavage over a 28-day period. Group 1 (negative control) received distilled water; Group 2 (positive control) received 30% ethanol at 7 mg/kg body weight; Group 3 (reference control) received 30% ethanol co-treated with the reference drug, clomiphene citrate; Groups 4 and 5 (test groups) received 30% ethanol co-treated with Rourea coccinea hydro-ethanolic extract at 200 and 400 mg/kg respectively. Testosterone hormone, sperm parameters and testicular histopathology were evaluated. Ethanol treatment induced a significant reduction (p |
| Databáze: | OpenAIRE |
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