High incidence and prevalence of MS in Møre and Romsdal County, Norway, 1950–2018
| Autor: | Johannes Sverre Willumsen, Jan Harald Aarseth, Kjell-Morten Myhr, Rune Midgard |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Adolescent Population Prevalence Norwegian Article Young Adult 03 medical and health sciences Multiple Sclerosis Relapsing-Remitting Sex Factors 0302 clinical medicine Humans Medicine Longitudinal Studies Registries 030212 general & internal medicine education Aged Biological Specimen Banks Retrospective Studies education.field_of_study Norway business.industry Incidence Incidence (epidemiology) Middle Aged Multiple Sclerosis Chronic Progressive language.human_language Neurology language Female Observational study Neurology (clinical) High incidence business 030217 neurology & neurosurgery Demography |
| Zdroj: | Neurology® Neuroimmunology & Neuroinflammation e713 Neurology: Neuroimmunology and neuroinflammation Neurology: Neuroimmunology and Neuroinflammation |
| ISSN: | 2332-7812 |
| DOI: | 10.1212/nxi.0000000000000713 |
| Popis: | Objective To determine prevalence and longitudinal trends in incidence of MS in Møre and Romsdal County, Western Norway, from 1950 to 2018. Methods Retrospective longitudinal population-based observational study. All patients diagnosed, or living, with MS in Møre and Romsdal were identified as incident or prevalent cases from local, regional, and national sources. We compiled the data in the Norwegian Multiple Sclerosis Registry and Biobank and used the aggregated data set to calculate incidence and prevalence rates using population measures obtained from Statistics Norway. Results On January 1, 2018, the estimated prevalence was 335.8 (95% CI, 314.1–358.5) per 100,000 inhabitants, with a female:male ratio of 2.3. From 1950 through 2017, we observed a considerable (p < 0.001) increase in average annual incidence rates from 2.1 (95% CI, 1.3–3.3) to 14.4 (95% CI, 11.9–17.3) per 100,000. From 2005 through 2017, the incidence among women increased from 17.1 (95% CI, 14.0–20.7) to 23.2 (95% CI, 18.7–28.5) per 100,000, whereas the incidence among men declined from 10.3 (95% CI, 7.9–13.2) to 5.9 (95% CI, 3.4–8.8) per 100,000. Conclusion Møre and Romsdal County in Western Norway has the highest prevalence of MS reported in Norway. The incidence has steadily increased since 1950, and during the latest 15 years, we observed opposing trends in sex-specific incidence rates. Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND), which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
| Databáze: | OpenAIRE |
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