Platelet Activation Markers and Soluble Adhesion Molecules in Patients with Systemic Lupus Erythematosus
| Autor: | Shosaku Nomura, Chie Yoshimura, Shirou Fukuhara, Yoshio Ozaki, Minori Nagahama, Hideo Kagawa |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Blood Platelets Male P-selectin Thrombomodulin medicine.medical_treatment Immunology Pathogenesis Humans Lupus Erythematosus Systemic Immunology and Allergy Medicine Platelet Platelet activation Annexin A5 Particle Size Lupus erythematosus business.industry Middle Aged Platelet Activation medicine.disease P-Selectin Cytokine Solubility Rheumatoid arthritis Cytokines Female Tumor necrosis factor alpha business Cell Adhesion Molecules Biomarkers |
| Zdroj: | Autoimmunity. 33:85-94 |
| ISSN: | 1607-842X 0891-6934 |
| Popis: | We assessed the role of platelet activation markers (PMPs, Annexin V and CD62P on activated platelets), cytokines (IL-1 beta, IL-4, IL-6, IFN- gamma, GM-CSF, and TNF alpha ), and soluble factors (sIL-2R, TM, sHLA-1, beta(2) -m, sVCAM-1, sPECAM-1, sP-selectin and sE-selectin) in vascular damage related to SLE. There were differences in the levels of PMPs and platelet activation markers between the SLE patients and controls (PMPs: 493+/-82 vs. 328+/-36, p |
| Databáze: | OpenAIRE |
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