Efficacy and Safety of Whole Blood Transfusion in Non-Trauma Patients

Autor:	Rahaf Alkhateb, Leslie Greebon, Brian J. Eastridge, Donald H. Jenkins, Charles P. Shahan, Randi Schaefer, Benjamin Axtman, Rachelle B. Jonas, Susannah E. Nicholson, Maxwell A. Braverman, Ronald M. Stewart, Alison Smith, Mark T. Foster
Rok vydání:	2021
Předmět:	Gastrointestinal bleeding education.field_of_study medicine.medical_specialty Resuscitation Future studies Adult patients business.industry Population General Medicine medicine.disease Academic institution Internal medicine medicine Etiology education business Whole blood
Zdroj:	The American Surgeon. :000313482110488
ISSN:	1555-9823 0003-1348
Popis:	Whole blood (WB) transfusion for trauma patients with severe hemorrhage has demonstrated early successful outcomes compared to conventional component therapy. The objective of this study was to demonstrate WB transfusion in the non-trauma patient. Consecutive adult patients receiving WB transfusion at a single academic institution were reviewed from February 2018 to January 2020. Outcomes measured were mortality and transfusion-related reactions. A total of 237 patients who received WB were identified with 55 (23.2%) non-trauma patients. Eight patients (14.5%) received pre-hospital WB. The most common etiology of non-traumatic hemorrhage was gastrointestinal bleeding (43.6%, n = 24/55). Approximately half of the non-trauma patients (n = 28/55) received component therapy. Transfusion-related events occurred in 3 patients. This study demonstrated that non-trauma patients could receive WB transfusions safely with infrequent transfusion-related events. Future studies should focus on determining if outcomes are improved in non-trauma patients who receive WB transfusions and defining specific transfusion criteria for this population.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b623cd528827ee4f6b553521aa550938 https://doi.org/10.1177/00031348211048831 Zobrazit plný text záznamu