Effect of low-dose argon irradiation on rate of wound closure

Autor:	William Janssen, Bradley H. Bethel, Timothy Johnston, James S. McCaughan
Rok vydání:	1985
Předmět:	Wound Healing medicine.medical_specialty integumentary system Open wounds Planimeter business.industry Lasers Guinea Pigs Low dose Dermatology Surgery medicine.anatomical_structure medicine Animals Laser exposure Wound closure Irradiation Argon business Wound healing Skin Subcutaneous tissue
Zdroj:	Lasers in Surgery and Medicine. 5:607-614
ISSN:	1096-9101 0196-8092
DOI:	10.1002/lsm.1900050609
Popis:	Four open circular wounds were made on the backs of each of ten guinea pigs by excising approximately 2-cm areas of full-thickness skin and subcutaneous tissue. Every 2 or 3 days, one of the four wounds was treated with 2 J/cm2 argon laser, one washed and treated, one only washed, and one receiving no treatment. The area of the remaining open wound was traced on a glass microslide. A tenth guinea pig received the same "treatments" but the laser was not turned on. The wounds receiving different treatments were randomly selected on different guinea pigs. The area of open wound remaining was measured with a planimeter, and the rate of healing was plotted for each. The numbers of days required for 50 and 75% healing were determined. All wounds were coded and the results determined by an independent observer. We found no difference in the rate of healing of any of these wounds and, under these experimental conditions, found no effect on the overall rate of wound healing by low-dose argon laser exposure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5e4663109c3939ef840b40e3ce1d0f5 https://doi.org/10.1002/lsm.1900050609 Zobrazit plný text záznamu Plný text