Undeclared Doping Substances are Highly Prevalent in Commercial Sports Nutrition Supplements

Autor: Luc J. C. van Loon, Willem Koert, Laila Spruijt, Erik Duiven, Olivier M. de Hon
Přispěvatelé: Humane Biologie, RS: NUTRIM - R3 - Respiratory & Age-related Health, Physiotherapy, Human Physiology and Anatomy, Human Physiology and Sports Physiotherapy Research Group
Jazyk: angličtina
Rok vydání: 2021
Předmět:
elite sport
health risks
Methylhexaneamine
01 natural sciences
chemistry.chemical_compound
0302 clinical medicine
ANABOLIC-ANDROGENIC STEROIDS
Tetrahydroisoquinolines
Prevalence
Medicine
doping violation
URINE
Orthopedics and Sports Medicine
Significant risk
DRUG
Testosterone Congeners
Doping in Sports
Adrenergic beta-Agonists
Drug Contamination
Fat loss
RC1200-1245
Sports
Research Article
HEPATOTOXICITY
Adrenergic beta-Antagonists
Physical Therapy
Sports Therapy and Rehabilitation
3-DIMETHYLAMYLAMINE
Muscle mass
Sports nutrition
Risk Assessment
spiking
dietary supplements
03 medical and health sciences
Alkaloids
STRYCHNINE
Contamination
Environmental health
Humans
PHENETHYLAMINES
business.industry
010401 analytical chemistry
Amphetamines
prohibited substances
030229 sport sciences
0104 chemical sciences
1
3-DIMETHYLAMYLAMINE
Androstadienes
METABOLITE
chemistry
Unintentional doping
GV557-1198.995
Sports medicine
General health
Boldione
business
human activities
DIETARY-SUPPLEMENTS
INGESTION
Zdroj: J Sports Sci Med
Journal of Sports Science and Medicine, Vol 20, Iss 2, Pp 328-338 (2021)
Journal of Sports Science and Medicine, 20(2), 328-338. Department of Sports Medicine, Medical Faculty of Uludag University
ISSN: 1303-2968
DOI: 10.52082/jssm.2021.328
Popis: Sports nutrition supplements have previously been reported to contain undeclared doping substances. The use of such supplements can lead to general health risks and may give rise to unintentional doping violations in elite sports. To assess the prevalence of doping substances in a range of high-risk sports nutrition supplements available from Dutch web shops. A total of 66 sports nutrition supplements - identified as potentially high-risk products claiming to modulate hormone regulation, stimulate muscle mass gain, increase fat loss, and/or boost energy - were selected from 21 different brands and purchased from 17 web shops. All products were analyzed for doping substances by the UK life sciences testing company LGC, formerly known as the Laboratory of the Government Chemist, using an extended version of their ISO17025 accredited nutritional supplement screen. A total of 25 out of the 66 products (38%) contained undeclared doping substances, which included high levels of the stimulants oxilofrine, beta-methylphenethylamine (BMPEA) and N,beta-dimethylphenethylamine (NBDMPEA), the stimulant 4-methylhexan-2-amine (methylhexaneamine, 1,3-dimethylamylamine, DMAA), the anabolic steroids boldione (1,4-androstadiene-3,17-dione) and 5-androstene-3 beta,17 alpha-diol (17 alpha-AED), the beta-2 agonist higenamine and the beta-blocker bisoprolol. Based upon the recommended dose and the potential variability of analyte concentration, the ingestion of some products identified within this study could pose a significant risk of unintentional doping violations. In addition to inadvertent doping risks, the prescribed use of 3 products (4.5%) could likely impose general health risks.
Databáze: OpenAIRE
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