100% Rapid Rescreening for Quality Assurance in a Quality Control Program in a Public Health Cytologic Laboratory
| Autor: | Celso di Loreto, Neuza Kasumi Shirata, Luzia Setuko Yamamoto, Maria da Gloria Mattosinho de Castro Ferraz, Lai W. S. Shih, Sonia Maria Miranda Pereira, Rosemeire O. L. Rodrigues, Yuriko Ito Sakai, Wiliam M. Pirani, Miria Dall’ Agnol, Maria Lúcia Utagawa, Camilo Lelis Feres, Adhemar Longatto Filho |
|---|---|
| Přispěvatelé: | Universidade do Minho |
| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
Histology Quality Assurance Health Care Low-Grade Squamous Intraepithelial Lesions Cytodiagnosis Medicina Básica [Ciências Médicas] Bethesda system Uterine Cervical Neoplasms Rapid rescreening Cervical intraepithelial neoplasia Sensitivity and Specificity Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Cytology Internal medicine medicine Humans Mass Screening Papanicolaou smear Cervical Intraepithelial Neoplasia Mass screening Vaginal Smears Gynecology Cervical cancer Medical Audit Science & Technology medicine.diagnostic_test business.industry Health care quality assurance Quality control Continuing education General Medicine Uterine Cervical Dysplasia 030224 pathology medicine.disease 3. Good health 030220 oncology & carcinogenesis Ciências Médicas::Medicina Básica Public Health Practice Female Laboratories business Quality assurance Brazil |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
| ISSN: | 1938-2650 0001-5547 |
| DOI: | 10.1159/000326252 |
| Popis: | To verij5 the efficacy of the quality control (QC) program in a cytologic laboratwy with a rapid rescreening (RR) protocol. To verij5 the efficacy of the quality control (QC) program in a cytologic laboratwy with a rapid rescreening (RR) protocol.RR, according to the Turret RR method, of all samples initially screened as negative at the Laboratory of Cytology, Adolfo Lutz Institute, was performed. The slides were reviewed for 60 seconds. Suspect smears were fully checked by 2 reviewers to determine the final diagnoses. A total of 2954 sequential cytologic results were considered in this study. Of the 2954, 2568 (86.9%) were considered initially negative according to our internal QC, and these cases underwent RR. Also, 10% were randomly selected from these negative cases for full reviewing. The internal QC in our laboratory includes review of cases selected according to clinical and cytomorphologic criteria.Among the 2954 total cases, QC detected 386 (13%) atypias with final diagnoses reported according to The Bethesda System 2001 as follows: 82 (2.18%) low grade squamous intraepithelial lesions (LSILs), 35 (1.18%) high grade squamous intraepithelial lesions (HSILs), 2 (0.06%) squamous cell carcinomas, 105 (3.5%) atypical cells of undetermined significance (ASC-US), 4 (0.12%) atypical endocervical cells (AECs) and 158 (5.3%) unsatisfactory samples. RR of 2568 smears initially considered negative selected 194 (7.5%) slides. Of the 194, 146 (75.3%) were negative, 28 (14.4%) ASC-US, 5 (2.6%) AEC, 1 (0.5%) LSIL and 14 (7.2%) unsatisfactory. Full review of a 10% random fraction of the 2568 cases interpreted as negative did not detect lesions but did detect 5 (1.95%) unsatisfactory samples.Internal QC used in our laboratory based on clinical and cytomorphologic criteria to select cases for review proved to be an efficient method of detecting HSIL and cervical cancer. The consensus basis of this program strongly limits the false positive and false negative rates and also provides subjects with continuing education. One hundred percent RR is more efficient than 10% full reviewing in detecting cervical abnormalities. |
| Databáze: | OpenAIRE |
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