Multiple Risk Factor Clustering and Risk of Hypertension in Japanese Male Office Workers
| Autor: | Wenjuan Li, Hideki Fukuda, Toshio Takatorige, Kozo Tatara, Kenji Suzuki, Noriyuki Nakanishi |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Health Toxicology and Mutagenesis Risk Assessment Prehypertension Japan Risk Factors Internal medicine Diabetes mellitus Cluster Analysis Humans Medicine Hyperuricemia Family history business.industry Hypertriglyceridemia Public Health Environmental and Occupational Health Odds ratio Middle Aged medicine.disease Obesity Occupational Diseases Cross-Sectional Studies Blood pressure Endocrinology Population Surveillance Hypertension business |
| Zdroj: | INDUSTRIAL HEALTH. 41:327-331 |
| ISSN: | 1880-8026 0019-8366 |
| DOI: | 10.2486/indhealth.41.327 |
| Popis: | Major risk factors associated with hypertension (a family history of hypertension, obesity, diabetes mellitus, hypercholesterolemia, hypertriglyceridemia, hyperuricemia, and increased white blood cell counts) were assessed in 5275 Japanese male office workers aged 23-59 years. After controlling for potential risk factors of hypertension, the odds ratio of hypertension compared with the absence of risk factors was 1.91, 2.65, 3.88, 6.54, and 8.18 for the presence of 1, 2, 3, 4, andor = 5 risk factors, respectively (P for trend0.001). Systolic and diastolic blood pressure levels also increased in a dose-dependent manner as the number of risk factors increased. Among men not taking antihypertensive medication, the adjusted mean differences in systolic and diastolic blood pressures (mmHg) were 11.2 and 9.2 between men with the presence ofor = 5 risk factors and men without risk factors, respectively. These results indicate that the accumulation of risk factors is highly associated with the increased risk of hypertension in Japanese men. |
| Databáze: | OpenAIRE |
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