In‐hospital respiratory viral infections for patients with established BPD in the SARS‐CoV‐2 era
| Autor: | Leif D. Nelin, Angela Murphy, Maleah Bates, Jodi Smathers, Matthew J. Kielt, Edward G. Shepherd |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty viruses viral infections Neonatal Lung Disease neonatology law.invention law Internal medicine bronchopulmonary dysplasia Medicine Infection control Humans Neonatology skin and connective tissue diseases Retrospective Studies Cross Infection business.industry Transmission (medicine) SARS-CoV-2 Infant Newborn COVID-19 Retrospective cohort study medicine.disease respiratory tract Intensive care unit Hospitals body regions medicine.anatomical_structure Bronchopulmonary dysplasia Pediatrics Perinatology and Child Health Cohort Original Article ORIGINAL ARTICLES business Respiratory tract |
| Zdroj: | Pediatric Pulmonology |
| ISSN: | 1099-0496 8755-6863 |
| Popis: | Objective Our objective was to test the hypothesis that in‐hospital respiratory viral infections (RVI) would be significantly lower in a cohort of patients with established bronchopulmonary dysplasia (BPD) exposed to a severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection prevention protocol when compared to historical controls. Study Design On April 1, 2020, we implemented a universal infection prevention protocol to minimize the risk of nosocomial SARS‐CoV‐2 transmission in a dedicated BPD intensive care unit. We performed a retrospective cohort study and included patients with established BPD, as defined by the 2019 Neonatal Research Network criteria, admitted to our center who underwent real‐time polymerase‐chain‐reaction RVI testing between January 1, 2015 and March 31, 2021. We excluded patients readmitted from home. We compared the proportion of positive tests to the number of tests performed and the distribution of viral respiratory pathogens in the pre‐ and post‐SARS‐CoV‐2 eras. Results Among 176 patients included in the study, 663 RVI tests were performed and 172 (26%) tests were positive. The median number of tests performed, measured in tests per patient per month, in the SARS‐CoV‐2 era was not significantly different compared to the pre‐SARS‐CoV‐2 era (0.45 vs. 0.34 tests per patient per month, p = .07). The proportion of positive RVI tests was significantly lower in the SARS‐CoV‐2 era when compared to the pre‐SARS‐CoV‐2 era (0.06 vs. 0.30, p |
| Databáze: | OpenAIRE |
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